174 Oblique earlobe crease as a physical examination finding in drug reaction with eosinophilia and systemic symptoms

نویسندگان

چکیده

Introduction: While drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is known to be associated facial swelling, this edema can challenging identify. This study evaluates the utility of a physical examination finding, oblique earlobe crease, support diagnosis DRESS. Design: retrospective case-control in which dermatologists evaluated for presence an crease patients diagnosed DRESS compared unmatched controls morbilliform reactions, Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN), or acute generalized exanthematous pustulosis (AGEP). Ear images were available chart 17 DRESS, 18 morbilliform, 5 SJS/TEN, AGEP included study. Results: The average age 56 51% male. When comparing vs. all other eruptions (low-risk AGEP), had sensitivity 81% (CI 64-93%) specificity 71% 57-83%) low-risk particular, 65% 46-80%) Conclusions: demonstrates that non-invasive indicator potential when as well eruptions. patient suspected eruption strong indication complete validated scoring assessment.

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2022

ISSN: ['1523-1747', '0022-202X']

DOI: https://doi.org/10.1016/j.jid.2022.05.181